CCNP Seminar: Christopher Rozell, PhD (Georgia Institute of Technology)

“Brain Biomarkers for Understanding Depression Recovery with Deep Brain Stimulation”

Speaker: Christopher Rozell
Professor, Executive Director of Institute for Neuroscience, Neurotechnology & Society (INNS)
Department of Electrical & Computer Engineering
Georgia Institute of Technology

Simultaneous advances in neurotechnology and data science have created new opportunities to measure, modulate and understand the neural activity underlying complex psychiatric disorders such as treatment resistant depression (TRD). Despite promising explorations of deep brain stimulation (DBS) as a therapy for TRD, one of the barriers to scaling this treatment is the lack of objective information supporting clinical decision making during recovery. I will describe our recent efforts collecting and analyzing longitudinal intracranial electrophysiology data from TRD patients undergoing subcallosal cingulate cortex (SCC) DBS, as well as our development of novel AI techniques to identify electrophysiology biomarkers of disease recovery state. Finally, I will show how this data-driven biomarker can potentially be used in clinical decision support through patient case studies, as well as shed light on the microcircuit structures and complex behaviors that underly TRD pathology and recovery.

Date and Time: Wednesday, June 3rd, 10-11am EDT (Eastern)
Zoom: https://princeton.zoom.us/j/6397147065

FYI, abstracts for previous talks are posted on the CCNP website: ccnp.princeton.edu. A list of upcoming seminars, job announcements, and other info about CCNP are available there as well.