Alzheimer’s Disease and Related Dementia Translational Work-in-Progress (ADRD-TWIP): Seungjoon Kim, PhD (Sangmi Chung Lab)

“Targeting Network Hyperexcitability in Alzheimer’s Disease via Human iPSC-Derived MGE Cell Transplantation: A K99/R00 Grant Application”

Speaker: Seungjoon Kim, PhD
Postdoctoral Research Associate in the Department of Neurosurgery at Rutgers Robert Wood Johnson Medical School, working in the laboratory of Dr. Sangmi Chung

Date and Time: Wed, July 1, 2026, 12-1 PM

Zoom: https://rutgers.zoom.us/j/94769804345?pwd=IMqJIIvuDmRl997R6O4U4NKbt6UWfs.1
Meeting code: 947 6980 4345
Passcode: 454288

This presentation will focus on a K99/R00 grant application proposing a circuit-repair strategy for Alzheimer’s disease. The project tests whether human iPSC-derived MGE-lineage interneuron grafts can restore hippocampal inhibitory balance, normalize early network hyperexcitability, and reduce subsequent tau propagation. This is intended as a work-in-progress discussion, and feedback on the grant structure, Specific Aims, experimental approach, and reviewer-response strategy would be greatly appreciated.